1-Adamantane Carboxaldehyde

  • 1-Adamantane Carboxaldehyde

In recent years, the biological activities and synthesis methods of amantadine derivatives have been further studied. SAXAGLIPTIN is a highly effective, selective, and competitive dipeptidyl peptidase IV (DPP-IV) inhibitor for the treatment of type 2 diabetes mellitus in adults. 1-Adamantane Carboxaldehyde can be used as the main raw material for the synthesis of saxagliptin.

It is generally believed that the functional groups of aldehydes are unstable and it is difficult to obtain high yield products through the usual oxidation reaction.The oxidants reported in the literature are relatively mild, but PCC oxidation pollutes the environment with heavy metal chromium, and the concentration of effective oxidant for TEMPO-oxidation is low, and 1-Adamantane methanol, which is difficult to prepare, is used as the raw material, so the industrial production is difficult.Our organic synthesizers can synthesize 1-Adamantane Carboxaldehyde in a safe, economical and green way under mild reaction conditions.